A Crash Course in Heart Disease

A Crash Course in Heart Disease

Heart disease is caused by everything these days. Sometimes it can seem easier to make a list of things that wouldn’t cause a heart condition. However, the heart disease statistics being released every day are often related to a few processes within your heart and vasculature. Understanding the science behind these types of heart disease[…]

Genetic Influence on  Beta-blocker Therapy

Genetic Influence on Beta-blocker Therapy

Beta-blockers have grown in influence since their properties were first discovered in 1958. They stand as staples on modern cardiovascular disease management. However, research into their receptor pathway has shown certain genetic factors can have a tremendous influence on beta-blocker pharmacodynamics. Mutations within the targeted receptors and associated regulatory proteins can change typical responses to[…]

Personalised Medicine is Ready for Practice

Personalised Medicine is Ready for Practice

  A man in his early fifties with hypertension appears at your office for review. He insists that he has been taking his medication as prescribed, but his blood pressure is still way above target. He has just spent the past weeks on an expensive medication that has done effectively nothing for him. This scenario[…]

Cardiovascular Disease

Cardiovascular Disease

Cardiovascular disease (CVD) is the general term used to describe conditions affecting both the heart and/or blood vessels. There are many types of CVD with the main four consisting of coronary artery disease (CAD), peripheral arterial disease (PAD), stroke and aortic disease. Today, we will discuss CVD in general along with causes, risk factors, how[…]

Genotyping?

Genotyping?

Did you ever wonder how a simple saliva sample can give you so much information? How can a drop of saliva indicate how long it takes your body to process caffeine? Or perhaps how depositing your saliva sample into a tube can be analysed to give you the likelihood of developing certain inherited conditions? …the[…]

No more ‘one size fits all’

No more ‘one size fits all’

Traditional methods of measuring cardiovascular risk take into account basic factors such as smoking status, age, blood pressure and cholesterol levels, but this information doesn’t paint a full picture of your cardiac health. Identifying if you have genetic traits associated with cardiovascular diseases can help your cardiologist tailor treatment to your genetics and minimise side[…]

The silent killers

The silent killers

Diseases can be inherited from our parents in several ways, but the two most common are dominant inheritance and recessive inheritance. Each cell in your body contains 23 pairs of chromosomes, which are made up of half your father’s and half your mother’s genes. These genes contain DNA instructions for how your body works and[…]

Personalised medicine

Personalised medicine

The field of personalised medicine is at the forefront of healthcare interest, yet this promising medical sector was non-existent beyond 20 years ago. The concept of personalised medical care has always been present, with clinicians striving to correctly match patients with treatments, however until recently it had not been possible to determine how individuals interact[…]