Changing the status quo

Initially, we wanted to see a change in the way healthcare was delivered to our close family members. Now we want to change the status quo. We believe that the future of healthcare lies in precision medicine coupled with advanced digital tools.

Our goal is to enable the use of medical technologies in everyday life so that we can improve the health and wellness of our clients.

Our DNA

We believe that revealing specific information encoded
within the DNA can help individuals take a step forward towards a personalised
healthy living and have an accurate, safer and more successful treatment and fitness regimen.

We believe that:
Genotype + Environment = Phenotype.

Physical characteristics are the result of a complex interaction between genes and environmental factors, and to make a sensible and actionable insight from Genetic information, we:

A.    Engage a qualified partner specialist whenever a clinical report is set to be sent out to one of our patients, in order to provide an accurate and actionable interpretation.

B.    Maintain the highest level of quality and privacy in our service.

C.    Communicate information in an understandable and UI friendly manner to the general public, whilst presenting information that is appropriate for further medical advice.

The need

It all started with a drug complication that Rightangled’s co-founder saw first hand in her family. Floriane's relative was experiencing drug side effects and responding poorly to an anticoagulant drug. The medication was Plavix (Clopidogrel) and the side effects were gum bleeding and bruises. After seeing her relative survive 5 strokes, it was clear that the drug was not working and a personalised treatment regimen was needed.

NHS funding and support

With Abdullah's knowledge about genetics and its influence on the way we respond to drugs, he and Flo decided to make genetic information more readily available. The concept of a new service design was born, to enable the use of genetic information within the medical practice, in a seamless, streamlined and affordable way. The project later presented to one of the NHS innovation adoption arms in the West Midlands, and it later received the backing and funding from NHS England.

The facts

The WHO estimates 50% of patients do not take prescribed medications for fear of side effects, patient-physician communication barriers, lack of information and limited healthcare access. Our service removes these factors, helping patients reach their optimal treatment regimen faster and for our partner doctors to have a complete risk profile for their patients that is objective and evidence-based. Such profiling is not only based on genetics but also the patient’s environmental risk factors.

Joined by our passion for health & wellbeing

Board of Directors

Abdullah Sabyah

Chariman and CEO

A scientist-entrepreneur and a healthcare professional, also a member of the British Heart Foundation Alliance, a member of the Clinical Pharmacogenomics Implementation Consortium in the US, and the inventor of a patent pending-technology for nucleic acid testing on a lateral flow assay (the patent is for a technology to detect DNA sequences in real-time).

Dr Sibtain Anwar

Non- Exec

Dr Sibtain Anwar a Senior Lecturer and Consultant in the Department of Perioperative Medicine at the Barts Heart Centre - Europe’s largest cardiovascular institution. He also sits on the Pain Medicine Council at the Royal Society of Medicine. He completed clinical training at Imperial College London, while also pursuing his research interests as an Honorary Fellow of the Academic Cardiology Unit at The National Heart and Lung Institute.

Professor Sir John Cunningham

Non-Exec

Lead Scientific Advisor, frontline NHS clinician at The Royal Free Hospital and Professor of Nephrology at UCL Medical School. Active researcher with over I00 papers published in peer reviewed journals. Honorary Fellow of Trinity Hall, University of Cambridge.

Dr Ahmed Merghani

Non-Exec

Ahmed graduated from Barts and the London Medical School in 2005, having also accomplished an intercalated BMedSci (hons) degree in Molecular Therapeutics. He attained membership of the Royal College of Physicians in 2008 and went on to achieve a National training number in Cardiology at the West Midlands Deanery. Since then, he has worked as a cardiology registrar in Birmingham and Coventry. In 2012, he pursued an MD degree at St. George’s, University of London.

Alexis Toft

Non-Exec

A former founder and MD of INEOS Healthcare which was based on the drug he invented. He raised £73mn, grew it from 3 to over 1,000 people involved working across 23 countries in 250 hospitals before exiting.