Be in control of your health.

Discover which hormonal therapy is best suited for you, learn how to minimise your risk of blood clots and how to reduce pregnancy-related complications.

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Let’s talk female health.

Reproductive Health

Understand which COCP will bring you the least risk.

Pregnancy

Ensure the best development for your with optimum folate levels.

Menopause

Reduce the side effects and risks of Hormone Replacement Therapy.

Venous Thrombosis

Learn your risk of the disease so oestrogen supplementation can be altered.

Who is this test for?

Anyone who is at risk of developing abnormal blood clots, and mainly women who are about to start taking the Pill or other types of Hormone Replacement Therapy.


Genes Testes:
MTHFR, Factor 2 and Factor 5.

Combined Oral Contraceptive Pill

The combined oral contraceptive pill (COCP) contains oestrogen and progesterone. There are different types of COCP which contain varying amounts of oestrogen. Oestrogen increases the stickiness of your blood so the development of thrombosis (blood clots) is more likely. Clots can obstruct blood flow in veins and lead to venous thrombosis. Blood clots can cause serious complications like strokes, heart attacks and pulmonary emboli. The test will determine your genetic predisposition to developing thrombosis when taking the combined oral contraceptive pill.

Hormone Replacement Therapy

Hormone replacement therapy (HRT) is taken during the menopause to prevent adverse side effects like hot flushes, mood swings, memory loss and many others.  HRT may contain oestrogen alone or combined oestrogen and progesterone. Oestrogen can increase the risk of blood clots leading to venous thrombosis. Blood clots can cause severe complications like strokes, heart attacks and pulmonary emboli. The test will determine your genetic predisposition to developing thrombosis when taking hormone replacement therapy orally.

Venous Thrombosis

Venous thrombosis is a disease whereby a blood clot forms within a vein and stops the flow of blood. The clot can break off into the bloodstream and get trapped in a smaller artery in the lungs or brain. Blocking an artery in the lungs or brain can cause life-threatening conditions, a pulmonary embolism or a stroke. These conditions can be prevented if a venous thrombosis is detected.

Folate Deficiency

Folate, also known as folic acid and vitamin B9, is a B vitamin required by the body to make DNA. Folate has many important functions in the body and can only be obtained through the diet. Folate deficiency is linked with an increased risk of developing cardiovascular disease, reduced fertility, abnormalities during pregnancy and cancer. Changes in the genes that metabolise folate can increase the risk of one of these complications arising. The test will determine your folate metabolism to allow you to make dietary changes. 

Homocysteine Abnormalities

Homocysteine is an amino acid, which in high levels can cause arterial damage and blood clots in the body. Increased levels of homocysteine are linked to an increased risk of cardiovascular disease, bone weakness and Alzheimer’s disease. The test will determine your predisposed homocysteine levels to allow you to make dietary changes.

What does the report look like?

You will receive 3 reports informing you about your Homocysteine predisposition and its impact on folate metabolism, your risk of Venous Thrombosis and if you have a risk to develop blood clots from taking Oestrogen supplements (The Pill and other Hormone Replacement Therapies).

Compare to other DNA tests

Your tailored action plan

Implementing tailored behaviour changes into your diet and lifestyle can influence your genetic risk.

Identify risk factors that cause blood clots.

Symptoms that may indicate onset of venous thrombosis.

Types of Combined Oral Contraceptive Pills that are best suited to you.

Signposting for further investigations.

Nutritional advice and dietary changes to alter folate levels.

Specific types of Hormone Replacement Therapy that will bring the least risk.

Stay Safe

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Do you share the results of my test with my GP?

Yes, but only if you give us your permission.

Does the test hurt or involve blood?

No. It is pain and blood free. You simply swab the inner side of your cheek, that’s it.

Can I get the test done on the NHS?

Generally, no. The cost of the test itself needs to be paid for privately. For private medical coverage, BUPA will fund this test.

Can this test be done on children?

We do not provide this service presently.