Rybelsus x30 Tablets (Semaglutide)

Novo Nordisk

Indicated for diabetes management but can aid in weight loss as off label.

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£ 149.99
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سعر البيع
£ 149.99
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Rybelsus Tablets (Semaglutide) - Rightangled
Rybelsus Tablets (Semaglutide) - Rightangled
Rybelsus Tablets (Semaglutide) - Rightangled
Rybelsus Tablets (Semaglutide) - Rightangled

Quick view Summary

  • Type of medicine

    GLP-1 receptor agonist

  • Effective within

    Within a few weeks.

  • Works by

    Reduces blood sugar and slows food passage.

  • Active ingredient


  • Strength

    3 mg, 7 mg, and 14 mg tablets

  • Common side effects

    Nausea, diarrhea, hypoglycemia (low blood sugar), stomach discomfort, and gastrointestinal upset.

  • Generic


  • Use with alcohol

    Avoid excessive alcohol consumption. Consult your doctor for guidance.

Rybelsus x30 Tablets (Semaglutide)


Rybelsus is a once-daily pill that can help lower blood sugar levels for people with type 2 diabetes. It works by mimicking the effects of a natural hormone and increasing insulin secretion, reducing glucose production, and helping with weight loss for improved overall health. The convenience of taking Rybelsus orally sets it apart from other similar medications, making it a more accessible option for many people.


To use Rybelsus effectively, start with a 3 mg tablet daily for the first month to improve tolerability. Depending on your response and tolerance, your prescriber may increase the dose to 7 mg and then possibly to 14 mg once daily. Take the tablet on an empty stomach with just half a glass of water (about 120 mL), and wait at least 30 minutes before eating, drinking, or taking other oral medications to ensure optimal absorption of semaglutide.


Rybelsus contains semaglutide, an active ingredient used to manage type 2 diabetes. It belongs to the GLP-1 receptor agonists class, enhancing insulin production, reducing glucagon secretion after meals, and slowing gastric emptying to help control blood sugar. Unique for being the first oral GLP-1 medication, Rybelsus offers a convenient alternative to injectable diabetes treatments.

Side effects

Rybelsus (semaglutide) may cause side effects including nausea, abdominal pain, diarrhea, decreased appetite, vomiting, and constipation.


Rybelsus is not suitable for individuals with allergies to semaglutide, type 1 diabetes, or diabetic ketoacidosis. It may cause severe gastrointestinal issues, and its use alongside sulfonylureas or insulin increases hypoglycemia risk. Rapid blood sugar improvement can exacerbate diabetic retinopathy. Not recommended for those under 18, and caution is advised for those pregnant, planning pregnancy, or breastfeeding. Interaction with medications like levothyroxine and warfarin requires careful monitoring. Driving or operating machinery is generally safe, though caution is advised if experiencing dizziness or hypoglycemia.

Patient information leaflet

Download patient information leaflet (PIL) on the link below:


Who can take Rybelsus?

Rybelsus, containing semaglutide, is designed for adults with type 2 diabetes to help control blood sugar in conjunction with diet and exercise. It's not meant for type 1 diabetes or diabetic ketoacidosis treatment. For weight management, semaglutide is available as Wegovy, specifically approved for this purpose. Consultation with a healthcare provider is key to deciding if Rybelsus is suitable for your health goals, especially for weight loss, as treatment plans are personalised.

Is Rybelsus® suitable for people with kidney issues?

Rybelsus® can be used in individuals with kidney issues, but caution is advised. It's crucial to discuss your kidney health with your doctor, as dose adjustments may be necessary to ensure your safety and optimal treatment outcomes.

What should I do if I miss a dose of Rybelsus?

If you miss a dose of Rybelsus, take it as soon as you remember on the same day. If it's already the next day, skip the missed dose and resume your regular dosing schedule. Do not take extra doses to make up for the missed one.

Can Rybelsus® cause interactions with other non-diabetes medications?

Rybelsus® may interact with certain medications, such as levothyroxine for thyroid disease or oral anticoagulants like warfarin. Inform your healthcare provider about all the medications you are taking to ensure safe and effective management of your health conditions.

Is Rybelsus® safe to use during pregnancy or while breastfeeding?

Rybelsus® is not recommended for use during pregnancy or breastfeeding due to potential risks to the unborn baby or infant. If you are planning to become pregnant or are currently pregnant, discuss alternative treatment options with your doctor.

Medically reviewed and published

This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead |

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