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Quick summary

Type of medicine

Topical Antihistamine Cream


Yes (Generic Versions Available)

Active Ingredient

Mepyramine Maleate

Effective within

Varies by Individual

Works by

Blocking Histamine Response

Side effects

Temporary Skin Irritation, Allergic Reactions

Medication details


Anthisan Cream 25g is a trusted over-the-counter (OTC) topical treatment formulated to provide relief from itching, pain, and discomfort associated with various insect bites and stings, as well as minor skin irritations. In this comprehensive guide, we will provide you with detailed information about Anthisan Cream 25g, including its description, directions for use, ingredients, potential side effects, and important warnings.

Insect bites and stings can be a common source of discomfort, causing itching, redness, and sometimes pain. Anthisan Cream contains the active ingredient mepyramine maleate, which is renowned for its antihistamine properties, making it an essential addition to your first aid kit for outdoor activities.


Proper application of Anthisan Cream is essential to maximize its effectiveness and ensure your safety. Here's how to use it correctly:
Clean the Affected Area: Before applying Anthisan Cream, clean the affected skin gently with mild soap and lukewarm water. Pat it dry thoroughly with a soft, clean towel.
Apply a Thin Layer: Squeeze a small amount of Anthisan Cream onto your fingertip. Apply a thin, even layer of the cream to the affected area(s) of the skin. Avoid using excessive amounts.
Gently Massage In: Using a gentle, circular motion, massage the cream into the skin until it is fully absorbed. Ensure that the cream is evenly distributed over the affected area.
Frequency of Application: The recommended frequency of application may vary depending on the severity of your symptoms. In most cases, Anthisan Cream can be applied up to three times daily. Follow the guidance provided on the product packaging or by your healthcare provider.
Duration of Use: Continue using Anthisan Cream as needed to alleviate itching, pain, and discomfort from insect bites and stings or minor skin irritations. It can be used as often as necessary. Consult with your healthcare provider for guidance on long-term use.
Avoid Contact with Eyes and Mucous Membranes: Be cautious to prevent contact with the eyes, nose, mouth, and mucous membranes. If accidental contact occurs, rinse thoroughly with water.


Anthisan Cream 25g contains the following active ingredient:
Mepyramine Maleate: Mepyramine maleate is an antihistamine that works by blocking the effects of histamine, a substance produced by the body in response to allergens, such as insect bites and stings. By blocking histamine, mepyramine maleate helps reduce itching, redness, and swelling associated with these reactions.
Inactive Ingredients:
The formulation may include other inactive ingredients to improve the texture, spreadability, and overall efficacy of the cream.

Side Effects

Anthisan Cream is generally well-tolerated, but some individuals may experience mild side effects. Common side effects may include:
Temporary Skin Irritation: Some users may experience temporary skin irritation, redness, or a burning sensation at the application site. This is typically mild and transient.
Allergic Reactions: While rare, some individuals may develop an allergic reaction to one or more components of Anthisan Cream. Allergic reactions can manifest as skin rash, itching, redness, or swelling. If you suspect an allergic reaction, discontinue use and seek medical attention.
Dry Skin: Prolonged use of Anthisan Cream on the same area may lead to dryness in that area.
It's important to note that these side effects are generally mild and temporary. If you experience severe or persistent side effects, discontinue use and consult your healthcare provider.


Before using Anthisan Cream, consider the following warnings:
Allergic Sensitivity: If you have a known allergy to mepyramine maleate or any of the ingredients in Anthisan Cream, do not use this product, and inform your healthcare provider. Do not apply in extensively broken skin, sunburnt skin or eczema.You may feel drowsy if this happens do not drive. For external use only on skin. Do not store above 30 C.
Do not ingest or apply it inside the mouth, nose, ears, or any internal body cavities.
Not for Treating Underlying Causes: Anthisan Cream provides relief from itching, pain, and discomfort caused by insect bites, stings, and minor skin irritations. It does not treat the underlying causes of these symptoms. If you experience severe or worsening symptoms or suspect a more significant medical issue, consult your healthcare provider.
Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using Anthisan Cream. While it is generally considered safe for external use, discuss its use in your specific situation.
Children and Infants: Anthisan Cream can be used in children and infants, but it should be done under the guidance of a healthcare provider. Ensure you follow recommended dosage and application guidelines for pediatric patients.
Consult with Your Healthcare Provider: If you have any specific medical conditions, are taking other medications, or have concerns about using Anthisan Cream alongside other treatments, consult your healthcare provider for personalized guidance.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Oct 5, 2023, 2:30 pm

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Please read our FAQs page to find out more.

Can Anthisan Cream be used for mosquito bites?

Yes, Anthisan Cream is effective for relieving itching and discomfort caused by mosquito bites. Its active ingredient, mepyramine maleate, helps reduce the itching sensation associated with mosquito bites.

Is Anthisan Cream suitable for children?

Anthisan Cream can be used in children, but it's essential to follow the recommended dosage and application guidelines for pediatric patients. Consult with a healthcare provider or pharmacist for guidance on using Anthisan Cream in children.

Can I use Anthisan Cream on bee stings?

Anthisan Cream is effective for soothing the itching and pain caused by bee stings. It can provide relief from bee sting-related discomfort. However, if you experience severe allergic reactions to bee stings, seek immediate medical attention.

Can Anthisan Cream be applied to multiple insect bites at once?

Yes, you can use Anthisan Cream to address multiple insect bites or stings simultaneously. Apply a thin layer of the cream to the affected area(s) and gently massage it in. Ensure that the cream is evenly distributed over all the bites.

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