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Quick summary

Type of medicine

Oral Spray


Active Ingredient

Effective within

Works by

Providing pain relief

Side effects

Medication details


Difflam Oral Spray is a medicated oral spray designed to provide relief from a range of oral and throat conditions. It is part of the non-steroidal anti-inflammatory drug (NSAID) class of medications. The active ingredient in Difflam Oral Spray is benzydamine hydrochloride, a substance known for its anti-inflammatory and analgesic (pain-relieving) properties.

Difflam Oral Spray's effectiveness lies in its ability to reduce inflammation and provide temporary relief from the discomfort associated with these oral conditions. It is widely available and can be an essential addition to your at-home oral care routine when used as directed. However, it is crucial to use this product responsibly and adhere to the provided directions for safe and effective relief.


To ensure effective and safe use of Difflam Oral Spray, follow these step-by-step directions:
Shake Well: Before each use, shake the Difflam Oral Spray bottle well to ensure proper mixing of the active ingredients.
Spray as Directed: Hold the spray bottle upright and point the nozzle toward the affected area in your mouth or throat.
Press the Pump: Depress the pump to release one or more sprays, depending on the severity of your symptoms and the dosage recommendations on the product label.
Use as Needed: You can use Difflam Oral Spray as needed, typically following the recommended dosage instructions on the product label or as advised by your healthcare provider.
Do Not Swallow Immediately: Avoid swallowing for at least 15 minutes after using the spray to allow it to provide optimal relief.
Always read and adhere to the instructions on the product label for specific dosing and usage guidelines.


Difflam Oral Spray contains a combination of active and inactive ingredients. The specific ingredients may vary depending on the formulation and flavor of the product. Below are some common ingredients you might find:
Active Ingredients:
Benzydamine Hydrochloride: This active ingredient possesses anti-inflammatory and analgesic (pain-relieving) properties, which help alleviate discomfort and reduce inflammation in the mouth and throat.
Inactive Ingredients: These ingredients contribute to the product's texture, taste, and overall stability. Common inactive ingredients may include:
Methyl Hydroxybenzoate (E218)
Saccharin Sodium
Polysorbate 20
Mouthwash Flavor
Please refer to the product packaging or label for the specific ingredients used in the Difflam Oral Spray product you have purchased.

Side Effects

Difflam Oral Spray is generally well-tolerated, but like any medication, it may cause side effects in some individuals. Common side effects associated with this product may include:
Temporary numbing or tingling sensation in the mouth or throat
Mild dryness or changes in taste
These side effects are typically mild and transient. If they persist or worsen, discontinue use and consult a healthcare provider.


Before using Difflam Oral Spray, consider the following important warnings and precautions:
Allergies: If you are allergic to any of the ingredients in Difflam Oral Spray, do not use the product.
Underlying Medical Conditions: If you have any underlying medical conditions or are taking other medications, consult a healthcare provider before using this product.
Pregnancy and Breastfeeding: Pregnant or breastfeeding individuals should seek advice from a healthcare professional before using Difflam Oral Spray.
Age Restrictions: Some Difflam Oral Spray products may have age restrictions. Ensure that the product is appropriate for the age of the user, especially for children.
Use as Directed: Follow the dosing and usage instructions on the product label or as directed by a healthcare provider. Do not exceed the recommended dose.
Not a Substitute for Treatment: While Difflam Oral Spray can provide temporary relief from various oral and throat conditions, it is not a substitute for treatment of underlying medical conditions that may be causing the symptoms.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Oct 5, 2023, 2:45 pm

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Please read our FAQs page to find out more.

Can I use Difflam Oral Spray for children?

Yes, Difflam Oral Spray is suitable for children but should be used under adult supervision and following age-appropriate dosing instructions. Consult the product label or a healthcare provider for guidance.

How often can I use Difflam Oral Spray in a day?

The frequency of use may vary based on your condition and the product's instructions. Typically, it can be used every 1.5 to 3 hours, but do not exceed the recommended dosage on the product label.

Can I use Difflam Oral Spray if I have allergies?

If you have known allergies, especially to the ingredients in Difflam Oral Spray, consult with a healthcare provider before using it to ensure it's safe for you.

Is Difflam Oral Spray safe for pregnant women?

Pregnant individuals should seek advice from a healthcare professional before using Difflam Oral Spray to assess its suitability for their specific condition.

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